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  • bsm-63121R核突觸蛋白α/β重組兔單抗

    Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively s

    更新時間:2025-03-05
    型號:bsm-63121R
    廠商性質(zhì):生產(chǎn)廠家
    瀏覽量:116
  • bsm-63120R基質(zhì)金屬蛋白酶-1重組兔單抗

    The matrix metalloproteinases (MMPs) are a family of at least eighteen secreted and membrane bound zincendopeptidases. Collectively, these enzymes can degrade all the components of the extracellular matrix, including fibrillar and non fibrillar collagens, fibronectin, laminin and basement membrane glycoproteins. In general, a signal peptide, a propeptide, and a catalytic domain containing the highly conserved zinc binding site characterizes the structure of the MMPs. In addition, fibronecti

    更新時間:2025-03-05
    型號:bsm-63120R
    廠商性質(zhì):生產(chǎn)廠家
    瀏覽量:73
  • bsm-63119R腺苷單磷酸活化蛋白激酶α1重組兔單抗

    The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-co

    更新時間:2025-03-05
    型號:bsm-63119R
    廠商性質(zhì):生產(chǎn)廠家
    瀏覽量:82
  • bsm-63118RB Raf重組兔單抗

    This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-s

    更新時間:2025-03-05
    型號:bsm-63118R
    廠商性質(zhì):生產(chǎn)廠家
    瀏覽量:98
  • bsm-63117R乙酰化組蛋白H4(K6)重組兔單抗

    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a mem

    更新時間:2025-03-05
    型號:bsm-63117R
    廠商性質(zhì):生產(chǎn)廠家
    瀏覽量:104
  • bsm-63116RG蛋白結(jié)合蛋白RAB11a重組兔單抗

    Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) a

    更新時間:2025-03-05
    型號:bsm-63116R
    廠商性質(zhì):生產(chǎn)廠家
    瀏覽量:110
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