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  • bsm-63115RDNA修復(fù)蛋白NBS1重組兔單抗

    Component of the MRE11/RAD50/NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA

    更新時(shí)間:2025-03-05
    型號(hào):bsm-63115R
    廠商性質(zhì):生產(chǎn)廠家
    瀏覽量:79
  • bsm-63114R表皮生長(zhǎng)因子受體3重組兔單抗

    The ErbB3 gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ErbB3 is a membrane-bound protein which has a neuregulin binding domain but not an active kinase domain. It can therefore bind this ligand but cannot convey a signal into the cell via protein phosphorylation. However it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to c

    更新時(shí)間:2025-03-05
    型號(hào):bsm-63114R
    廠商性質(zhì):生產(chǎn)廠家
    瀏覽量:88
  • bsm-63113R磷酸化成視網(wǎng)膜細(xì)胞瘤基因重組兔單抗

    The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.$nRb is a tumor suppressor gene which functions as a negative regula

    更新時(shí)間:2025-03-05
    型號(hào):bsm-63113R
    廠商性質(zhì):生產(chǎn)廠家
    瀏覽量:84
  • bsm-63112R磷酸化DNA修復(fù)蛋白NBS1重組兔單抗

    Component of the MRE11/RAD50/NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA

    更新時(shí)間:2025-03-05
    型號(hào):bsm-63112R
    廠商性質(zhì):生產(chǎn)廠家
    瀏覽量:84
  • bsm-63111R磷酸化表皮生長(zhǎng)因子受體重組兔單抗

    The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript var

    更新時(shí)間:2025-03-05
    型號(hào):bsm-63111R
    廠商性質(zhì):生產(chǎn)廠家
    瀏覽量:90
  • bsm-63109R單甲基化組蛋白H3(R18)重組兔單抗

    Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most spec

    更新時(shí)間:2025-03-05
    型號(hào):bsm-63109R
    廠商性質(zhì):生產(chǎn)廠家
    瀏覽量:84
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